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In conclusion, we provided a benchmark for error correction algorithms that can be used in PGM data applications for viral genome sequencing. We suggested the combined use of Pollux and Fiona as a better choice for its performance in both the real HBV Ion Torrent PGM and simulated data. However, vigorous algorithms need to be developed for PGM data in the setting of distinguishing low-frequency variants and sequencing errors.
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This is one of the (rare) occasions in which I don't agree with IMDb ratings. This movie should have been rated much-much higher. This is why I decided to write a review about it- not a common thing for me. It's one of these movies that you either love or hate, but I think that everyone who has seen it, must agree that aesthetically it reaches perfection. Ultra high tech, sleek, perfectly shot, kind of futuristic environments, with each scene being so beautifully framed, it's almost surreal. At certain points I just wished I could jump right into the screen and into the movie, because what I saw, was where I would like to spend the rest of my life!The story is not confusing, if you pay attention to it, which I admit, is a hard thing to do, when your attention is always drawn to the gorgeous imagery. I think most people who didn't like the film, blame the lack of significant action, but I do not consider this to be an action film per se..It is a cerebral film, a riddle within a riddle, a dive into the subconscious. Soo-hyun Kim delivers an amazing performance, I cannot praise him enough. The rest of the cast do their roles justice as well, Sung-min Lee in particular, is especially sinister.All in all, the Koreans never seize to amaze me, they have raised the bar of film making so high, I doubt that any other country will surpass them in the near future. I've been watching Korean movies for years, and these guys shine brightly, while the others fade into oblivion... Hollywood? Please...Hollywood has been dead and buried for years now. All Hollywood does these days, is recycle the same scenarios, wrapped with the current (politically correct) trends each time, or make action hero movies for adolescents. They have stopped creating Art sometime in the '80s...If you are looking for a mystery film wrapped in futuristic led light, with amazing performances, then this is the film for you. If, on the other hand, what you seek is non stop action, then you might want to challenge yourself with this movie- it's worth the watch. Just keep an open mind (and eyes) and experience it...
So, why two out of ten stars for this movie? Because the performances were really good so I had to give them that.However, the story was ... hmm ... complicated. It didn't make sense most of the time and when it finally did, it just wasn't worth the two hours plus that were wasted watching it. Some of the mature scenes were, I guess, there to make it more edgy, but, for real, there were just unnecessary. The action scenes were okay and the visuals really nice, but they seemed to focus more on them than the story, which was just thinly spread through this lengthy film.So, overall, two out of ten.
As I've watched this movie, I've got to realize that it's not that bad as it was publicized (like the wor